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Open Access Research article

Roles of CUP-5, the Caenorhabditis elegans orthologue of human TRPML1, in lysosome and gut granule biogenesis

Erin M Campbell and Hanna Fares*

Author Affiliations

Department of Molecular and Cellular Biology, Life Sciences South Room 531, University of Arizona, Tucson, AZ 85721, USA

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BMC Cell Biology 2010, 11:40  doi:10.1186/1471-2121-11-40

Published: 11 June 2010

Additional files

Additional file 1:

Fig. S1 - Late endocytic and lysosome-related organelles in developing intestinal cells of wild type embryos. Supplementary figure showing images of wild type embryos stained to detect various compartments in developing intestinal cells.

Format: TIFF Size: 20MB Download file

Open Data

Additional file 2:

Fig. S2 - CUP-5 protein localization in developing intestinal cells. Supplementary figure showing images of wild type embryos expressing GFP::CUP-5 and stained to detect gut granules in developing intestinal cells.

Format: TIFF Size: 19.4MB Download file

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Additional file 3:

Fig. S3 - Late endocytic and lysosome-related organelles in developing intestinal cells of cup-5 mutant embryos. Supplementary figure showing images of cup-5 mutant embryos stained to detect various compartments in developing intestinal cells.

Format: TIFF Size: 19MB Download file

Open Data

Additional file 4:

Fig. S4 - Late endocytic organelles in developing intestinal cells of cup-5 mutant embryos. Supplementary figure showing images of cup-5 mutant embryos stained to detect YP170::GFP and LMP-1::RFP in developing intestinal cells.

Format: TIFF Size: 19.6MB Download file

Open Data