Sal B ameliorated renal interstitial fibrosis induced by HgCl2 in model rat. (A) Masson's trichrome staining for assessing renal interstitial fibrosis. HgCl2 induced an increase of collagen in kidney section. Sal B and Vit E treatments reduced collagen deposition. (B) Kidney Hyp content determined by Jamall's method. Hyp content of kidneys was increased significantly in the model group as compared with the normal group. In contrast, Sal B and Vit E treatments significantly decreased kidney Hyp content.
Wang et al. BMC Cell Biology 2010 11:31 doi:10.1186/1471-2121-11-31