Table 1

Summary of ID expression analysis, centrosome abnormalities and abnormal mitoses.

Cell Line

ID1

ID2

ID3

ID4

% cells with n > 2 centrosomes

% mitoses

% abnormal mitoses


C33A

+

+

(+)

-

11.2 (± 1.8)

6.8 (± 4.5)

1.3 (± 0.9)

JURKAT

+

++

++

-

10.5 (± 1.1)

3.3 (± 0.5)

0.9 (± 0.5)

T47D

(+)

++

-

-

9.7 (± 1.8)

5.5 (± 1.7)

1.2 (± 0.2)

HeLa

+

(+)

(+)

-

9.3 (± 0.9)

6.9 (± 0.2)

0.8 (± 0.2)

CaSki

+

-

-

-

8.8 (± 1.1)

11.0 (± 4.7)

3.8 (± 1.2)

HaCaT

+

(+)

(+)

-

8.7 (± 1.9)

4.2 (± 1.6)

1.7 (± 0.1)

HCT-15

+

+

(+)

-

8.3 (± 3.3)

1.2 (± 1.6)

0.3 (± 0.6)

MDA-MB-453

(+)

(+)

(+)

-

6.6 (± 2.0)

3.2 (± 0.2)

1.2 (± 0.2)

MCF-7

-

(+)

-

-

6.5 (± 2.3)

4.3 (± 1.4)

0.5 (± 0.2)

SiHa

+

(+)

(+)

-

6.5 (± 0.4)

5.3 (± 1.4)

1.5 (± 0.2)

293T

-

(+)

-

-

6.5 (± 1.9)

5.3 (± 0.4)

1.2 (± 0.2)

H-2171

+

-

(+)

-

6.0 (± 0.5)

8.0 (± 1.0)

1.2 (± 0.2)

MDA-MB-468

-

+

(+)

-

5.8 (± 1.8)

2.5 (± 0.7)

0.7 (± 0.7)

HL-60

(+)

++

-

-

5.3 (± 1.2)

6.0 (± 1.0)

0.7 (± 0.2)

U937

(+)

++

-

-

5.2 (± 0.9)

7.3 (± 3.3)

1.1 (± 1.2)

U2OS

(+)

(+)

-

-

4.9 (± 1.1)

3.3 (± 0.5)

1.2 (± 0.7)

NCI-H295

-

(+)

-

-

4.7 (± 0.4)

3.0 (± 0.4)

0.3 (± 0.5)

KASUMI-1

(+)

+

-

-

2.9 (± 0.2)

2.3 (± 1.4)

0.7(± 0.9)


Cell lines are lined up starting with highest rate of centrosomal abnormalities. +: high expression; (+): intermediate expression; -: Low expression or not detectable.

Manthey et al. BMC Cell Biology 2010 11:2   doi:10.1186/1471-2121-11-2

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