Mechanical loading improves the colony-forming ability of young, adult, and old ADSCs. A. Number of colonies after 5 day culture of ADSCs, which were pre-exposed to mechanical strain (PS) or as non-strain controls (NS). Colony size was defined as in Figure 1. ***1: P < 0.001, *2: P < 0.03. N = 6. B. Increased numbers of medium (M) and large colonies (L) due to pre-exposure to mechanical strain in 8-day ADSC cultures. Each point represents the average of triplicate measurements of ADSCs from one mouse. N = 7.
Huang et al. BMC Cell Biology 2010 11:18 doi:10.1186/1471-2121-11-18