PDGF induces SMC migration through anILK-dependent pathway. A) Inhibition of ILK protein expression with 20 nM ILK siRNA markedly decreased SMC migration in response to PDGF-BB. Data represents three independent experiments (n = 3 culture plates in each replicate) and the value is presented as mean ± STDEV where P < 0.05 was considered significant. B) ILK inhibition decreased the number of migrated SMCs into the site of injury in response to PDGF-BB treatment as compared to the control group (contorl siRNA). Original magnification, ×40. Data present one of three independent experiments.
Esfandiarei et al. BMC Cell Biology 2010 11:16 doi:10.1186/1471-2121-11-16