Quantitative evaluation of adipogenic (A) and osteogenic (B) differentiation in murine bone marrow (BM; A1, B1), perirenal adipose tissue (PAT; A2, B2), and mediastinal stromal tissue (MST; A3, B3) cells cultivated via monolayer (black bars) and "mesenchymal microspheres" (MMS; grey bars). Early differentiation by three-dimensional MMS prior to the application of specific induction media is represented at time point 0 d. Mean values ± SEM derived from independent samples per experimental group (n = 3) are shown. Significant differences are indicated: * = p ≤ 0,05; ** = p ≤ 0,01; *** = p ≤ 0,001.
Böhrnsen et al. BMC Cell Biology 2009 10:92 doi:10.1186/1471-2121-10-92