Hydroxyurea treatment affects both replication factory number and size. High resolution Z stacks from cells treated with hydroxyurea, or untreated, were processed as for figure 4 (A). The average maximum axial width (B) and number of objects (C) are shown, calculated exactly as in figure 3.
Cseresnyes et al. BMC Cell Biology 2009 10:88 doi:10.1186/1471-2121-10-88