Additional file 5.

Analysis of the charge distribution of tau40. Arg and Lys are regarded as positively charged, and Asp and Glu as negatively charged. Thus, for the purposes of calculation, these four residues were considered as the charged components. Sequentially from the N- to the C-terminus, a window of 19 amino acid residues as a group was taken to calculate the average charge as described by Wang and coworkers [26]. Different regions of tau40 protein are indicated by different colours.

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He et al. BMC Cell Biology 2009 10:81   doi:10.1186/1471-2121-10-81