Email updates

Keep up to date with the latest news and content from BMC Cell Biology and BioMed Central.

Open Access Research article

RNAi mediated acute depletion of Retinoblastoma protein (pRb) promotes aneuploidy in human primary cells via micronuclei formation

Angela Amato1, Laura Lentini1, Tiziana Schillaci1, Flora Iovino2 and Aldo Di Leonardo1*

Author Affiliations

1 Dipartimento di Biologia Cellulare e dello Sviluppo "A. Monroy", Università di Palermo, viale delle Scienze, Palermo, Italy

2 Dipartimento di Discipline Chirurgiche e Oncologiche, Laboratorio di Patofisiologia Cellulare e Molecolare Università di Palermo, Palermo, Italy

For all author emails, please log on.

BMC Cell Biology 2009, 10:79  doi:10.1186/1471-2121-10-79

Published: 2 November 2009

Additional files

Additional file 1:

FACScan analysis of colcemid treated human fibroblasts. Flow citometry analysis showed increase in G2/M of the cells treated with colcemid up to 16 hours. Cell cycle distribution was determined by using FACScanto (Becton Dickinson) and analyzed by ModFit software (Verity).

Format: PNG Size: 824KB Download file

Open Data