GX1-rmhTNFα inhibits tumor growth with decreased systemic toxicity by enhancing tumor vascular permeability. (A) GX1-rmhTNFα significantly delayed tumor growth. (B) GX1-rmhTNFα led to less weight loss than rmhTNFα. (C) GX1-rmhTNFα induced a greater leakage of the dye in the tumor parenchyma than rmhTNFα. Bars, SD. * p < 0.05, **p < 0.01.
Chen et al. BMC Cell Biology 2009 10:63 doi:10.1186/1471-2121-10-63