The effect of compound 1 on growth factor induced BAEC proliferation. Cells were seeded in a 6-well plate in the numbers shown and the effect of compound 1 on growth factor-induced proliferation (25–75 ng/ml) was determined as described below. Columns 1 seeded cells; 2 DMSO alone; 3 growth factor alone; 4–7 compound 1 at concentrations of 1.43, 14.3, 28.6 and 71.5 μM. Values which differ significantly (p < 0.05) from growth factor alone are indicated by *. Results are the mean of three experiments.
Hussain et al. BMC Cell Biology 2009 10:30 doi:10.1186/1471-2121-10-30