Figure 6.

Summary schematic of the observed mobilization response of NEDD4L-C2(+) in response to a Ca2+ stimulus. NEDD4L-C2(+)-C943A that lacks ubiquitin ligase activity does not mobilize to the plasma membrane in step 4, and prevents β-ENaC transit to the plasma membrane in step 4.

Garrone et al. BMC Cell Biology 2009 10:26   doi:10.1186/1471-2121-10-26
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