Table 1

Cytotoxic activity of INA-UV treatment measured on different cancer cell lines by the MTS assay

Cell line

Human cancer types

IC50 ± SE (μM)*


MCF7

Breast adenocarcinoma

20.6 ± 8.8

HeLa

Cervical cancer

11.2 ± 1.7

U251

Glioma

15.4 ± 1.0

SKOV-3

Ovarian carcinoma

17.6 ± 1.0

SKBR-3

Breast carcinoma

7.8 ± 1.5

KB3-1

Epidermoid carcinoma

16.0 ± 0.7

KBV1

Epidermoid carcinoma overexpressing Pgp

12.3 ± 4.4

293

Epithelial cell line from embryonic kidney

8.6 ± 0.9

293/MRP1

Epithelial cell line from embryonic kidney overexpressing MRP1

7.3 ± 1.0

SupT1

T lymphoblastoid

4.9 ± 0.6


* Seven independent measurements were performed and analyzed together. IC50 values were computed by fitting a four-parameter nonlinear regression model with R statistical software [57]. The standard error (SE) represents the 95% confidence interval.

Viard et al. BMC Cell Biology 2009 10:21   doi:10.1186/1471-2121-10-21

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