Table 1 |
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|
Cytotoxic activity of INA-UV treatment measured on different cancer cell lines by the MTS assay |
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|
Cell line |
Human cancer types |
IC50 ± SE (μM)* |
|
|
||
|
MCF7 |
Breast adenocarcinoma |
20.6 ± 8.8 |
|
HeLa |
Cervical cancer |
11.2 ± 1.7 |
|
U251 |
Glioma |
15.4 ± 1.0 |
|
SKOV-3 |
Ovarian carcinoma |
17.6 ± 1.0 |
|
SKBR-3 |
Breast carcinoma |
7.8 ± 1.5 |
|
KB3-1 |
Epidermoid carcinoma |
16.0 ± 0.7 |
|
KBV1 |
Epidermoid carcinoma overexpressing Pgp |
12.3 ± 4.4 |
|
293 |
Epithelial cell line from embryonic kidney |
8.6 ± 0.9 |
|
293/MRP1 |
Epithelial cell line from embryonic kidney overexpressing MRP1 |
7.3 ± 1.0 |
|
SupT1 |
T lymphoblastoid |
4.9 ± 0.6 |
|
|
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|
* Seven independent measurements were performed and analyzed together. IC50 values were computed by fitting a four-parameter nonlinear regression model with R statistical software [57]. The standard error (SE) represents the 95% confidence interval. |
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|
Viard et al. BMC Cell Biology 2009 10:21 doi:10.1186/1471-2121-10-21 |
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