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Open Access Research article

HAC stability in murine cells is influenced by nuclear localization and chromatin organization

Daniela Moralli, David YL Chan, Andrew Jefferson, Emanuela V Volpi and Zoia L Monaco*

Author Affiliations

Wellcome Trust Centre for Human Genetics, University of Oxford, Roosevelt Drive, Oxford, OX3 7BN, UK

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BMC Cell Biology 2009, 10:18  doi:10.1186/1471-2121-10-18

Published: 6 March 2009

Additional files

Additional file 1:

HAC colocalization with the chromocenters. To shows that SM1-1 (C6) do not colocalize with chromocenters (white arrows), but can colocalize with mouse minor satellite (yellow arrows), several cells from this clone are shown, following hybridization with 17α (red signals) and minor satellite probes (green signals). The bottom panels display the same cells, stained with DAPI to show the chromocenters distribution, and the outline of the HAC in blue.

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