Figure 8.
The BioPNG Gel Plot. (A) The gel plot of the original scanned data for the Renal Cell Carcinoma Affymetrix
X3P GeneChip. The arrow indicates a chip with a corrupted file format, causing the
intensity values to be read incorrectly. The Bioconductor program that parsed the
chips did not catch this error, but it became clear after visualizing the intensity
distributions. (B) The gel plot of the normalized and artifact-replaced data output
by caCORRECT. These distributions are clearly well-aligned, but the same data parsing
problem persisted without causing any post-processing algorithms to generate errors.
Stokes et al. BMC Bioinformatics 2008 9(Suppl 6):S18 doi:10.1186/1471-2105-9-S6-S18 |