Table 6

Examples of confused contexts in the TF & PPI dataset

Correct
Predicted
Example

PPI
TF
Transcription Factor IIH (TFIIH) and p300 act cooperatively to enhance Vpr effects on glucocorticoid receptor transactivation.
PPI
TF
These studies show that VES induces growth inhibition of BT-20 cells through a mechanism that involves cyclin A-negative regulation of E2F-mediated transcription.
PPI
TF
Adenovirus E1A protein represses activation by Vpr by competing for binding to p300, suggesting that p300 is required for activation of HIV transcription by Vpr.
TF
PPI
It plays a role in HOMEOSTASIS of GLUCOSE and controls expression of GLUT2 PROTEIN.
TF
PPI
Mutations in hepatocyte nuclear factor 1-beta are associated with renal CYSTS and MATURITY-ONSET DIABETES MELLITUS type 5.

Yang et al. BMC Bioinformatics 2008 9(Suppl 3):S11   doi:10.1186/1471-2105-9-S3-S11