Figure 9.

Comparison between sequence and structure base predictors. Overall accuracy (Q3) and mean correlation coefficient (<C>) of the structure-based (3D) and of the sequence-based (SEQ) methods relative to highly buried residues with RSA≤10 (30% of DB3D), on mutations with 10<RSA≤50 (39% of DB3D) and exposed residue RSA>50 (31% of DB3D).