BMC Bioinformatics

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GeneChaser: Identifying all biological and clinical conditions in which genes of interest are differentially expressed

Rong Chen1,2,3, Rohan Mallelwar4, Ajit Thosar4, Shivkumar Venkatasubrahmanyam1,2,3 and Atul J Butte1,2,3*

Author Affiliations

1 Stanford Center for Biomedical Informatics Research, Department of Medicine, Stanford University School of Medicine, 251 Campus Drive, Stanford, CA 94305, USA

2 Department of Pediatrics, Stanford University School of Medicine, 251 Campus Drive, Stanford, CA 94305, USA

3 Lucile Packard Children's Hospital, 725 Welch Road, Palo Alto, CA 94304, USA

4 Optra Systems Pvt. Ltd, 1, "Dnyanesh", CTS No. 1179/3, Modern College Road, Shivajinagar, Pune, 411 005, India

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BMC Bioinformatics 2008, 9:548 doi:10.1186/1471-2105-9-548

Published: 18 December 2008

Additional files

Additional file 1:

Top conditions in which Nanog was significantly differentially expressed. A single gene search result shows the top 12 biological and clinical conditions in which Nanog, or one of its orthologs, was differentially expressed (q ≤ 0.05, fold > 2).

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Open Data

Additional file 2:

Agent comparisons showing differential expression of Nanog. A single gene search result shows that Nanog, or one of its orthologs, was differentially expressed after drug treatments in four studies (q ≤ 0.05, fold > 2).

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Open Data

Additional file 3:

Mouse studies showing differential expression of Nanog, Oct4, Sox2, and Lin28. A multiple gene search result shows that Nanog, Oct4, Sox2, and Lin28 were differentially expressed in five mouse studies (q ≤ 0.05).

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Open Data

Additional file 4:

Human studies showing differential expression of Nanog, Oct4, Sox2, and Lin28. A multiple gene search result shows the top 14 human studies in which Nanog, Oct4, Sox2, and Lin28 were differentially expressed (q ≤ 0.05).

Format: PDF Size: 52KB Download file

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Open Data