Table 3

Comparison of cross-validation results for predicting promoters and enhancers.

Combination

Promoter PPVa (standard deviation)

Enhancer PPV (standard deviation)


HMM method using 6 histone signaturesb

97.87% (1.06)

93.52%(1.83)


HMM method using 2 histone signaturesc

95.46% (2.82)

94.06% (0.89)


Heintzman et al. using 6 histone signatures

96%

78%


Heintzman et al. using 2 histone signatures

95%

85%


aPositive predictive value (PPV) = true prediction/(true prediction + wrong prediction) and standard deviation are calculated.

b6 histone signatures: H4ac, H3ac, H3Kme1, H3K4me2, H3K4me3, H3

c2 histone signatures: H3Kme1, H3K4me3

Won et al. BMC Bioinformatics 2008 9:547   doi:10.1186/1471-2105-9-547

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