Corra-generated hierarchical clustering of yeast phosphopeptide analyses. Phosphopeptides were isolated from two yeast strains, one wild type, and the other an Ark1 protein kinase knockout, and analyzed in triplicate on a very high mass accuracy LC-MS platform, as described under Methods. The 22,562 Corra-detected features that aligned across 3 or more LC-MS runs were used to produce this hierarchical cluster that well distinguished between the two samples, as expected.
Brusniak et al. BMC Bioinformatics 2008 9:542 doi:10.1186/1471-2105-9-542