Research article
Predicting biological system objectives de novo from internal state measurements
-
* Corresponding author: Jason A Papin papin@virginia.edu
- † Equal contributors
1 Department of Biomedical Engineering University of Virginia Box 800759, Health System Charlottesville, VA 22908 USA
2 Genomatica, Inc. San Diego, CA 92121 USA
3 Department of Chemical Engineering The Pennsylvania State University University Park, PA 16802 USA
BMC Bioinformatics 2008, 9:43 doi:10.1186/1471-2105-9-43
Published: 24 January 2008Additional files
Additional File 1:
Saccharomyces cerevisiae metabolism. A description of the S. cerevisiae central metabolic network from [22], including reaction and metabolite listing, is provided.
Format: PDF Size: 311KB Download file
This file can be viewed with: Adobe Acrobat Reader
Additional File 2:
Clustering in BOSS. The clustering component of the BOSS framework, as implemented in MATLAB, is described.
Format: PDF Size: 730KB Download file
This file can be viewed with: Adobe Acrobat Reader
Additional File 3:
Evaluating data integration in BOSS. BOSS is applied to a prototypic system designed to illustrate the ability of the framework to infer an objective function by synthesizing information from multiple experimental conditions.
Format: PDF Size: 396KB Download file
This file can be viewed with: Adobe Acrobat Reader