Resolution: standard / high
Figure 2.
The FOSTA filtering process: homologues are identified by BLAST-ing against the UniProtKB/Swiss-Prot
database (filtering stage (1)); these are then filtered to retain only those with
similar function (filtering stage (2)); finally one protein per species (the FEP,
or functionally equivalent protein) is chosen using a hierarchy of functional matches
to eliminate functionally diverged homologues (FDHs) (filtering stage (3)).
McMillan and Martin BMC Bioinformatics 2008 9:418 doi:10.1186/1471-2105-9-418
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