|
Resolution: standard / high Figure 6.
Error detected by MisPred routine for Conflict 2. ENSXETP00000040601 of Xenopus tropicalis corresponds to the frog ortholog of Ephrin receptor A7, but lacks a typical transmembrane
helix between its extracellular FN3 and cytoplasmic Pkinase domains. The mispredicted
sequence was corrected by identifying the missing transmembrane sequence using frog
EST sequences such as EL820950 [GenBank:EL820950]. The alignment shows the regions containing the transmembrane helices of Gallus gallus Ephrin receptor A7 [RefSeq:NP_990414], ENSXETP00000040601 and ENSXETP00000040601_corrected.
The predicted transmembrane helices of NP_990414 and ENSXETP00000040601_corrected
are in red and underlined, the mispredicted region of ENSXETP00000040601 is in italics.
Nagy et al. BMC Bioinformatics 2008 9:353 doi:10.1186/1471-2105-9-353 |