Table 4 |
||
|
Top five over-represented GO biological process categories obtained with three different integartion models |
||
|
GO (BP) categories |
P values |
# of genes |
|
|
||
|
MAID |
||
|
organismal physiological process |
8.90E-007 |
41 |
|
immune response |
4.96E-006 |
24 |
|
response to biotic stimulus |
1.41E-005 |
25 |
|
defense response |
1.81E-005 |
24 |
|
response to stimulus |
1.98E-004 |
39 |
|
Rhodes et al. |
||
|
response to biotic stimulus |
8.12E-006 |
11 |
|
immune response |
1.84E-005 |
10 |
|
response to pest, pathogen or parasite |
2.12E-005 |
8 |
|
response to other organism |
2.54E-005 |
8 |
|
defense response |
3.54E-005 |
10 |
|
Parmigiani et al. |
||
|
glyoxylate metabolism |
4.44E-003 |
1 |
|
sphingolipid catabolism |
4.44E-003 |
1 |
|
sphingomyelin metabolism |
4.44E-003 |
1 |
|
sphingomyelin catabolism |
4.44E-003 |
1 |
|
coagulation |
8.37E-003 |
2 |
|
|
||
|
Top five enriched GO categories obtained with, MAID, Rhodes et al., and, Parmigiani et al. In each case genes had to be up (or down) regulated |fold| ≥ 1.5 in HCV samples compared to Normal with an expected number of false positives E(F P) = 10 for each gene list. |
||
|
Borozan et al. BMC Bioinformatics 2008 9:305 doi:10.1186/1471-2105-9-305 |
||
