Figure 2.

ROC₅₀ scores of various methods for fold recognition at the fold level. The x-axis represents the ROC₅₀ score and the y-axis represents the proportion of proteins with better performance than the corresponding ROC₅₀ score. The mean ROC₅₀ score using NMF features is 0.44, while the corresponding figures are 0.21, 0.20, and 0.10 for original PPA features, HHsearch, and PSI-BLAST, respectively. At > 0.95 ROC₅₀ scores, 22% of protiens with NMF features correctly detect remotely related proteins, whereas original PPA features detect almost none.