Tissue-specific gene expression and TF interactions. (A) An example of gene expression profile. The gene RPE65 (RefSeq ID: NM_000329; UniGene ID: Hs.2133; Ensembl ID: ENSG00000116745) is preferentially expressed in the eye with an expression enrichment value greater than 13. (B) Distribution of -log10(p) values for 307 tissue-specific TF interactions in the eye. The most significant is the interaction between FOXJ2 and POU3F2, with a -log10(p) value greater than 39 (p-value < 10-39).
Liu et al. BMC Bioinformatics 2008 9:271 doi:10.1186/1471-2105-9-271