Table 3 |
|||||
|
Summary of ICAtrait linkage and Gene Ontology analyses |
|||||
|
Trait |
QTL |
N |
X/T |
P-adj |
GO over-representation |
|
|
|||||
|
1 |
XII: 423789, XV: 179409 |
189 |
58/1017 |
< 0.001 |
mitochondrion |
|
2 |
III: 201166 |
45 |
5/8 |
< 0.001 |
mating-type specific/mating-type specific transcriptional control |
|
3 |
0 |
77 |
26/108 |
< 0.001 |
nitrogen compound biosynthesis, amine biosynthesis |
|
4 |
XII: 473036 |
12 |
4/5 |
< 0.001 |
asparagine catabolism |
|
5 |
0 |
3 |
NA |
NA |
NA |
|
6 |
II: 554641 |
1448 |
54/83 |
< 0.001 |
mitochondrial ribosome |
|
7 |
V: 422588 |
63 |
26/94 |
< 0.001 |
retrotransposon nucleocapsid/VLP/Virus-like particle |
|
8 |
III: 90986 |
49 |
8/13 |
< 0.001 |
nitrogen compound biosynthesis, amine biosynthesis |
|
9 |
X: 329085 |
22 |
4/6 |
< 0.001 |
alcohol dehydrogenase activity/alcohol dehydrogenase (NAD) activity, fermentation |
|
10 |
XIV: 449639 |
304 |
225/1017 |
< 0.001 |
mitochondrion, mitochondrial ribosome |
|
11 |
XII: 660992 |
83 |
22/37 |
< 0.001 |
sterol metabolism, sterol biosynthesis |
|
12 |
V: 116389 |
9 |
3/13 |
< 0.001 |
pyrimidine base biosynthesis |
|
13 |
XV: 563943 |
184 |
125/1017 |
< 0.001 |
oxidative phosphorylation/respiratory- chain phosphorylation, mitochondrion |
|
14 |
VIII: 111686 |
42 |
16/100 |
< 0.001 |
conjugation, sexual reproduction |
|
15 |
IX: 141014 XIII: 395391 |
8 |
NA |
NA |
NA |
|
16 |
IV: 1501558, XI: 298361, |
47 |
15/84 |
< 0.001 |
helicase activity, telomerase-independent |
|
XII: 824230, XII: 1056097 |
telomere maintenance |
||||
|
17 |
IV: 527484 |
6 |
3/3 |
< 0.001 |
sodium ion transport/sodium transport/sodium:solute transport |
|
18 |
XII: 423789, XV: 179409 |
32 |
2/2 |
0.015 |
NA |
|
19 |
XIII: 40447 |
14 |
4/5 |
< 0.001 |
acid phosphatase activity |
|
20 |
0 |
63 |
NA |
NA |
NA |
|
|
|||||
|
For each ICAtrait, we report the number and position of any significant linkages detected, the number of traits that are significantly correlated with a specific ICAtrait (N), the number of correlated traits that have the over-represented GO attribute (X), the total number of traits that have this attribute (T) and also the over-represented GO annotation term. Three of the 20 show no over-representation of biological functions while for remaining 16 both previously described and novel GO categories with associated eQTL were detected. Analysis of ICAtrait 7 and 9 are described in more detail in the text. |
|||||
|
Biswas et al. BMC Bioinformatics 2008 9:244 doi:10.1186/1471-2105-9-244 |
|||||
