BMC Bioinformatics

official impact factor 3.03

This article is part of the supplement: Otto Warburg International Summer School and Workshop on Networks and Regulation

Open Access Review

Computational analyses of eukaryotic promoters

Michael Q Zhang

  • Correspondence: Michael Q Zhang

Author Affiliations

Cold Spring Harbor Laboratory, 1 Bungtown Road, Cold Spring Harbor, NY 11724, USA

BMC Bioinformatics 2007, 8(Suppl 6):S3 doi:10.1186/1471-2105-8-S6-S3

Published: 27 September 2007

Abstract

Computational analysis of eukaryotic promoters is one of the most difficult problems in computational genomics and is essential for understanding gene expression profiles and reverse-engineering gene regulation network circuits. Here I give a basic introduction of the problem and recent update on both experimental and computational approaches. More details may be found in the extended references. This review is based on a summer lecture given at Max Planck Institute at Berlin in 2005.