Example RDF queries. (a) shows a part of the SeRQL query that finds pairs of worm (C. elegans) proteins homologous to pairs of interacting proteins in yeast (C. cervisiae), i.e. "interologs". b) shows part of the corresponding query results. (c) shows the SeRQL query that explores the relationship between gene essentiality and the level of pseudogene content in yeast, which is one feature that might be hypothesized to be associated with essentiality, with queries of the joined YeastHub and LinkHub data. (d) shows the yeast pseudogenes found, interestingly only one. (e) shows part of the list of pseudogenes found in human homologs for a similar query; the full list is long, around 20000, consistent with there being many known pseudogenes in humans.
Smith et al. BMC Bioinformatics 2007 8(Suppl 3):S5 doi:10.1186/1471-2105-8-S3-S5