Table 1

The reactions not associated with pathways in HumanCyc but for which there was a corresponding pathway in KEGG.

HumanCyc Reaction

KEGG Pathway and corresponding reaction

cholesterol + an acyl-CoA = cholesterol ester + coenzyme A

R0146 EC 2.3.1.26 in Bile acid biosynthesis pathway

O2 + NADPH + cholesterol = H2O + NADP^± + 7α-hydroxycholesterol

R01453 EC 1.14.13.- in biosynthesis of steroids

NADP+ + cholesterol = 7-dehydro-cholesterol + NADPH

R01456 EC 1.3.1.21 in biosynthesis of steroids pathway

O2 + a reduced adrenal ferredoxin + cholesterol = H2O + an oxidized adrenal ferredoxin + 4-methylpentanal + pregnenolone

R02724 EC 1.14.15.6 in C21-Steroid hormone metabolism

The numbers prefixed by R are the reaction numbers in the KEGG database.

Luciano and Stevens BMC Bioinformatics 2007 8(Suppl 3):S3   doi:10.1186/1471-2105-8-S3-S3