Additional File 1.

Phylogenetic distribution of functional target sites. Inferred selection pattern distributions p() for all miRNAs that are conserved in all vertebrate (panel a) and all fly (panel b) species. Each row corresponds to a miRNA seed and each column corresponds to one of the variables ρ_ω(k) – where k indicates the internal node in the tree and ω indicates which of the subtrees are under selection – that parametrize p() (see Methods). The miRNAs are sorted by the inferred total fraction ρ of putative target sites that is under selection in at least one other species.

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Gaidatzis et al. BMC Bioinformatics 2007 8:69   doi:10.1186/1471-2105-8-69