Additional file 1.

Background frequencies for residue variability estimates: BLOSUM revisited – Supplementary Material. The supplement contains the reference distribution Q, structural classification of used proteins according to SCOP, and additional comparative analysis of the method presented here with methods already available in the literature.

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Mihalek et al. BMC Bioinformatics 2007 8:488   doi:10.1186/1471-2105-8-488