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Background frequencies for residue variability estimates: BLOSUM revisited

I Mihalek1,2*, I Reš1 and O Lichtarge1

1 Department of Molecular and Human Genetics, Baylor College of Medicine, One Baylor Plaza, Houston, TX 77030, USA

2 Bioinformatics Institute, Agency for Science, Technology and Research (A*STAR), 30 Biopolis Street, #07-01 Matrix, 138671, Singapore

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BMC Bioinformatics 2007, 8:488 doi:10.1186/1471-2105-8-488

Published: 27 December 2007

Additional files

Additional file 1:

Background frequencies for residue variability estimates: BLOSUM revisited – Supplementary Material. The supplement contains the reference distribution Q, structural classification of used proteins according to SCOP, and additional comparative analysis of the method presented here with methods already available in the literature.

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