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Open Access Highly Accessed Software

Dendroscope: An interactive viewer for large phylogenetic trees

Daniel H Huson*, Daniel C Richter, Christian Rausch, Tobias Dezulian, Markus Franz and Regula Rupp

Author Affiliations

Center for Bioinformatics Tübingen (ZBIT), Eberhard-Karls-Universität Tübingen, Sand 14, 72076 Tübingen, Germany

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BMC Bioinformatics 2007, 8:460  doi:10.1186/1471-2105-8-460

Published: 22 November 2007

Abstract

Background

Research in evolution requires software for visualizing and editing phylogenetic trees, for increasingly very large datasets, such as arise in expression analysis or metagenomics, for example. It would be desirable to have a program that provides these services in an effcient and user-friendly way, and that can be easily installed and run on all major operating systems. Although a large number of tree visualization tools are freely available, some as a part of more comprehensive analysis packages, all have drawbacks in one or more domains. They either lack some of the standard tree visualization techniques or basic graphics and editing features, or they are restricted to small trees containing only tens of thousands of taxa. Moreover, many programs are diffcult to install or are not available for all common operating systems.

Results

We have developed a new program, Dendroscope, for the interactive visualization and navigation of phylogenetic trees. The program provides all standard tree visualizations and is optimized to run interactively on trees containing hundreds of thousands of taxa. The program provides tree editing and graphics export capabilities. To support the inspection of large trees, Dendroscope offers a magnification tool. The software is written in Java 1.4 and installers are provided for Linux/Unix, MacOS X and Windows XP.

Conclusion

Dendroscope is a user-friendly program for visualizing and navigating phylogenetic trees, for both small and large datasets.