BMC Bioinformatics

official impact factor 3.03

Open Access Highly Access Methodology article

A statistical method to incorporate biological knowledge for generating testable novel gene regulatory interactions from microarray experiments

Peter Larsen1, Eyad Almasri2, Guanrao Chen3 and Yang Dai2*

Author Affiliations

1 Core Genomics Laboratory at University of Illinois at Chicago, 845 West Taylor Street Chicago, IL 60607, USA

2 Department of Bioengineering (MC063), University of Illinois at Chicago, 851 South Morgan Street, Chicago, IL 60607, USA

3 Department of Computer Science, University of Illinois at Chicago, 851 South Morgan Street, Chicago, IL 60607, USA

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BMC Bioinformatics 2007, 8:317 doi:10.1186/1471-2105-8-317

Published: 29 August 2007

Additional files

Additional file 1:

Distribution of number of annotated genes. The data provides the distribution of numbers of annotated genes distribution of at the selected 23 GO MF annotations by GO Slim Mapper.

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Additional file 2:

Examples of histograms of GO MF annotation pairs. The figures provide evidences that GO annotation pairs follow normal distribution.

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