BMC Bioinformatics

official impact factor 3.03

Open Access Highly Access Methodology article

Semantic integration to identify overlapping functional modules in protein interaction networks

Young-Rae Cho1*, Woochang Hwang1, Murali Ramanathan2 and Aidong Zhang1

Author Affiliations

1 Department of Computer Science and Engineering, State University of New York, Buffalo, NY, USA

2 Department of Pharmaceutical Science, State University of New York, Buffalo, NY, USA

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BMC Bioinformatics 2007, 8:265 doi:10.1186/1471-2105-8-265

Published: 24 July 2007

Additional files

Additional file 1:

Modularization results of the networks weighted by semantic similarity. Ten different output sets of modules were generated by the flow-based algorithm. The input was the protein interaction network weighted by semantic similarity. To assess the accuracy of modules, the average f-measure and the average -log(p-value) were measured for each output set.

Format: PDF Size: 61KB Download file

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Open Data

Additional file 2:

Modularization results of the networks weighted by semantic interactivity. Ten different output sets of modules were generated by the flow-based algorithm. The input was the protein interaction network weighted by semantic interactivity. To assess the accuracy of modules, the average f-measure and the average -log(p-value) were measured for each output set.

Format: PDF Size: 61KB Download file

This file can be viewed with: Adobe Acrobat Reader

Open Data