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Overlap between clusters in physical interaction network and GO annotation |
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| Biological process (public GOA) |
Biological process (MedScan GOA) |
Biological process (combined GOA) |
Cellular component (public GOA) |
Molecular function (public GOA) |
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|
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| 54 |
50 |
54 |
49 |
54 |
|
A total of 54 network clusters, each containing between 8 and 82 proteins were obtained in the given realization of Potts network clustering method [31]. The statistical significance of the overlap between every cluster and every GO group of a given annotation was evaluated using Fisher's Exact Test by computing the probability that the cluster and a GO group, drawn from the same set of ~10000 proteins at random, have the overlap not less than the observed one. The table shows the number of network clusters overlapping with at least one GO group in a given annotation with a p-value less than 0.001. | ||||
Daraselia et al. BMC Bioinformatics 2007 8:243 doi:10.1186/1471-2105-8-243 |
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