Table 2

Description of the dataset.

Number of Proteins (in KEGG)

Number of possible functional linkages examined

Number of positives

Pathways

E. coli

Yeast

E. coli

Yeast

E. coli

Yeast

All Pathways

1,347

1,191

708,645

635,628

43,968

35,674

Carbohydrate metabolism

292

241

33,153

26,565

5,450

4,859

Energy metabolism

135

134

8,128

8,001

2,113

3,060

Lipid metabolism

83

100

2,080

4,656

602

1,232

Nucleotide metabolism

108

113

5,050

5,995

3,686

5,082

Amino acid metabolism

237

216

20,100

19,900

3,328

3,620

Metabolism of cofactors and vitamins

146

113

7,875

5,253

1,085

740

Translation

80

185

3,081

15,400

1,761

10,792

Membrane transport

259

24,531

16,834

Folding, sorting, and degradation

82

2,926

809

Jothi et al. BMC Bioinformatics 2007 8:173   doi:10.1186/1471-2105-8-173