|
Average classification accuracies using TAS statistics on Endogenous and Transfected data test sets and the subcellular markers used |
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| Organelle |
Endogenous Accuracy |
Transfected Accuracy |
Endogenous Marker |
Transfected Marker |
|
|
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| Nucleus |
97.4% |
92.6% |
DAPI |
myc-nbp-45 (txreg I920050F21) |
| Cytoplasm |
- |
95.5% |
- |
GFP-V5 |
| Endoplasmic Reticulum |
90.8% |
82.5% |
anti-PDI |
ICAT-GFP |
| Golgi |
98.2% |
87.7% |
anti-Beta-COP |
GCC-GFP |
| Plasma Membrane |
93.3% |
82.4% |
anti-EGFR |
myc-Lysophosphatidic acid receptor |
| Endosome |
93.9% |
88.1% |
anti-SNX1 |
rab5a-GFP |
| Lysosome |
96.5% |
76.5% |
Lysotracker |
myc-chloride channel 7 (5330412O18) |
| Peroxisome |
95.9% |
95.7% |
anti-catalase |
ALD |
| Mitochondria |
92.6% |
76.2% |
Mitotracker |
myc-carntine/acylcarnitine translocase |
| Actin Cytoskeleton |
97.8% |
92.3% |
Phalloidin |
YFP-actin |
| Microtubules |
92.8% |
92.1% |
anti alpha-tubulin |
YFP-tubulin |
|
The accuracies (percentage of true positive predictions) are averaged over 1000 random division of each data set into 4/5ths for training and 1/5th for testing. The overall average classification accuracies on the test sets were 94.4% and 86.3% on the endogenous and transfected sets, respectively. | ||||
Hamilton et al. BMC Bioinformatics 2007 8:110 doi:10.1186/1471-2105-8-110 |
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