Figure 5.

GO TreePrune – This node-like tree display allows the user to filter out nodes and thus reduce the complexity of a tree by specifying the p- and E-value as well as the user-defined number of genes in the end node. A GO term is represented by a sectored pie, where the red sector shows the percentage of the inputted genes associated with the term. The individual genes associated with each term are displayed in the right panel by single clicking the term. The annotation of a term can be turned on or off by double clicking the term. Each term is movable with mouse drag, which is convenient when working on a dense tree or with many annotations. The tree diagram can be zoomed and moved by holding down the right or left button of the mouse, respectively.