Table 6

Protein kinase- substrate pairs used in the estimating the probabilities of predictions based on Scansite scores

Protein kinase *

Substrate protein (source)

Number of all serine and threonine residues

Number of known phosphorylation sites


PKA

Myelin basic protein (bovine)

22

6

PKA

Vimentin (mouse)

64

5

PKA

Vasodilator-stimulated phosphoprotein (human)

41

3

PKC

Pleckstrin (human)

36

3

PKC

MARCKS (human)

35

3

CaMK2

Myelin basic protein (bovine)

22

4

CaMK2

Vimentin (mouse)

64

2

CK2

DARPP-32 (bovine)

22

3

CK2

Alpha-S1 casein (bovine)

19

3

CK2

DNA topoisomerase II (S. cerevisiae)

172

9

CK1

Alpha-S2 casein (bovine)

30

6

CK1

Glycogen synthase, muscle (rabbit)

93

4


* Protein kinase-substrate pairs selected from Phosphobase [70].

Brinkworth et al. BMC Bioinformatics 2006 7:47   doi:10.1186/1471-2105-7-47

Open Data