Figure 5.

The pseudocode of MOFA. In this study, we set the binding score z = 2. This means that a TF is regarded as binding to a gene if (1) the p-value for the TF to bind the gene is ≤ 0.001 in the ChIP-chip data or (2) 0.001<p ≤ 0.01 and the TF-gene pair have a temporal relationship. Moreover, we require that the number of genes in a module must be ≥ 5. This value is the same as that in GRAM algorithm [21] for comparison purpose.