|
Resolution: standard / high Figure 4.
Log transformation of absent call signals shows a strong reduction in variance, leading to a greater proportion of sufficiently powered probe sets through greater precision, but less accuracy (higher expected false positives). Log transformation of data is a commonly used method to reduce variance, and thus increase precision. Taking the same data set shown in Figure 3 and log transforming the data effectively increases the proportion of probe sets that are sufficiently powered at low numbers of arrays per group.
Seo and Hoffman BMC Bioinformatics 2006 7:395 doi:10.1186/1471-2105-7-395 |