Table 5

Top ten genes in the ethanol (first three columns) and non-ethanol (last three columns) signatures along with their rank and expression ratios.

Gene Name

Rank

Expression Ratio

Gene Name

Rank

Expression Ratio


yaiD

1

298.3

ygjK

1

-20.9

argH

2

170.0

tktA

2

-5.2

mngA

3

85.6

dsbC

3

-8.5

plsC

4

76.9

cvrA

4

-2.3

caiA

5

300.3

nrfE

5

-11.9

yebU

6

51.6

yehI

6

-19.2

ylbF

7

29.9

ybbA

7

-4.1

nrfG

8

46.8

evgS

8

-16.2

yaiY

9

27.6

ynfE

9

-14.4

pnp

10

4.9

pqiB

10

-3.7


Expression ratios are defined as follows. For the ethanol signature, as the average expression level of a gene in the 4 ethanol-challenged cultures divided by the average expression level in the 8 cultures not exposed to ethanol. For the non-ethanol signature, the ratio was inverted and a negative sign was included to indicate that these genes are down-regulated as the result of the ethanol challenge.

Rollins et al. BMC Bioinformatics 2006 7:377   doi:10.1186/1471-2105-7-377

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