BMC Bioinformatics

official impact factor 3.03

Open Access Research article

Detecting the limits of regulatory element conservation and divergence estimation using pairwise and multiple alignments

Daniel A Pollard1, Alan M Moses1, Venky N Iyer2 and Michael B Eisen1,2,3,4*

Author Affiliations

1 Graduate Group in Biophysics, University of California, Berkeley, CA 94720, USA

2 Department of Molecular and Cell Biology, University of California, Berkeley, CA 94720, USA

3 Department of Genome Sciences, Genomics Division, Ernest Orlando Lawrence Berkeley National Lab, Berkeley, CA 94720, USA

4 Center for Integrative Genomics, University of California, Berkeley, CA 94720, USA

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BMC Bioinformatics 2006, 7:376 doi:10.1186/1471-2105-7-376

Published: 14 August 2006

Additional files

Additional File 1:

This file, in GFF2 format [91], contains the coordinates of the 36 enhancers used in this study in Drosophila melanogaster release 4 coordinates [92].

Format: GFF Size: 5KB Download file

Open Data

Additional File 2:

This text file contains horizontal counts matrices and vertical frequency matrices for each of the eight transcription factors used in this study.

Format: TXT Size: 4KB Download file

Open Data