Research article
A powerful method for detecting differentially expressed genes from GeneChip arrays that does not require replicates
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* Corresponding author: Anne-Mette K Hein a.hein@imperial.ac.uk
Dept. of Epidemiology and Public Health, Imperial College London, Norfolk Place, London, UK
BMC Bioinformatics 2006, 7:353 doi:10.1186/1471-2105-7-353
Published: 20 July 2006Additional files
Additional File 1:
Supplementary Figure 1 – Plots of the curves (f, see text) fitted to the histogram counts of P(dg < 0) values for pairwise within and between condition comparisons – AffyU133A Data set. A curve is plotted for each pair of arrays in the AffyU133A data set (left: within condition comparisons, right: between condition comparisons). The plots show the expected shape of uni-modality and smoothly decreasing tails under the null (left) and deviations from this under this pattern, in terms of excess values near 0 and 1, for the between condition comparisons (right).
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