Research article
Computational expression deconvolution in a complex mammalian organ
-
* Corresponding author: Lewis A Chodosh chodosh@mail.med.upenn.edu
- † Equal contributors
1 Departments of Cancer Biology, Medicine, and Cell & Developmental Biology, and the Abramson Family Cancer Research Institute, University of Pennsylvania, 612 BRB II/III, 421 Curie Blvd, Philadelphia, PA 19104, USA
2 Department of Pathology and Laboratory Medicine, University of Pennsylvania, 613A Stellar-Chance Labs, 422 Curie Blvd., Philadelphia, PA 19104, USA
BMC Bioinformatics 2006, 7:328 doi:10.1186/1471-2105-7-328
Published: 3 July 2006Additional files
Additional File 1:
Sources of Affymetrix MG-U74Av2 raw data used in the identification of tissue-specific genes
Format: DOC Size: 41KB Download file
This file can be viewed with: Microsoft Word Viewer
Additional File 2:
Genes significantly regulated in mouse mammary gland at pregnancy compared to nulliparity. An Excel file containing all genes on Affymetrix MG-U74Av2 arrays that were analyzed by comparing mammary tissues of d18 pregnant and 10 wk nulliparous mice. The file lists the change calls of the genes before ("Pre-adj") and after ("Post-adj") taking the estimated changes of cell compartment sizes into account.
Format: XLS Size: 2.7MB Download file
This file can be viewed with: Microsoft Excel Viewer
Additional File 3:
GO terms significantly associated with genes activated by pregnancy. An Excel file containing the GO terms significantly associated with genes whose expression were considered to be significantly regulated, both before ("Pre-adj") and after ("Post-adj") taking estimated changes in cell compartment sizes into account in the mammary glands of d18 pregnant and 10 wk nulliparous mice.
Format: XLS Size: 19KB Download file
This file can be viewed with: Microsoft Excel Viewer
Additional File 4:
Genes regulated by oncogenic Ras activation. An Excel file containing genes on Affymetrix MG-U74Av2 arrays that were analyzed by comparing mammary tissues at d4 and d0 following Ras activation. The file lists the change calls of genes before ("Pre-adj") and after ("Post-adj") taking the estimated changes of cell compartment sizes into account.
Format: XLS Size: 2.7MB Download file
This file can be viewed with: Microsoft Excel Viewer
Additional File 5:
GO terms significantly associated with genes activated by oncogenic Ras. An Excel file containing all GO terms significantly associated with genes whose expressions were considered to be significantly regulated, both before ("Pre-adj") and after ("Post-adj") adjusting for estimated changes in cell compartment sizes following four days of Ras activation in the mammary gland.
Format: XLS Size: 29KB Download file
This file can be viewed with: Microsoft Excel Viewer