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A new measure for functional similarity of gene products based on Gene Ontology

Andreas Schlicker*, Francisco S Domingues, Jörg Rahnenführer and Thomas Lengauer

Department of Computational Biology and Applied Algorithmics, Max-Planck-Institute for Informatics, Stuhlsatzenhausweg 85, 66123 Saarbrücken, Germany

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BMC Bioinformatics 2006, 7:302 doi:10.1186/1471-2105-7-302

Published: 15 June 2006

Additional files

Additional file 1:

Detailed results from sections "Comparing biological processes and molecular functions" and "Comparison of funSim and sequence similarity". Table S1: The 50 biological processes from fungi with lowest simRel values compared to mammalian processes. Table S2: The molecular functions from Mycobacterium with lowest simRel values compared to mammalian functions. Figure S1: Distribution of the MFscore (A), BPscore (B), funSim score (C) for different sets of protein pairs using GO annotation with all evidence codes.

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