|
Public codon optimization softwares. |
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| Name |
Features |
Comment |
Reference |
|
|
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| RE |
Macintosh |
[49] |
|
| GMAP |
RE |
[50] |
|
| CalcGene |
CUT |
[51] |
|
| COD OP |
CUT, RE, DO |
Unix perl |
[52] |
| DNA Works |
CUT, RE, DO |
Web browser |
[53] |
| Codon Optimizer |
CUT, RE |
[54] |
|
| Prot2DNA |
CUT, RE, mSeq, Rep |
Precursor to Gene Designer |
[4] |
| Gene2Oligo |
DO |
Web browser |
[55] |
| UpGene |
CUT, DO |
[56] |
|
| GeMS |
CUT, RE, mSeq, DO |
Web browser |
[57] |
| JCat |
CUT, RE |
Web browser |
[58] |
| Synthetic Gene Designer |
CUT, RE, DO |
Web browser |
[59] |
|
Software with features similar to the codon optimization module of Gene Designer. CUT indicates that one or more codon usage tables are referenced during reverse translation of the protein sequence. RE indicates that restriction endonuclease sites can be identified and silently removed and/or inserted. Rep indicates that repeats and/or inverted repeats can be silently removed. mSeq indicates that mRNA secondary structures can be silently removed. DO identifies software that includes a module for the design of oligonucleotides for gene synthesis | |||
Villalobos et al. BMC Bioinformatics 2006 7:285 doi:10.1186/1471-2105-7-285 |
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