Additional File 1.

• VAST and SHEBA heat maps • Complete heat map of VAST and SHEBA, obtained for a Pcli cutoff value of 2.5 and a Zscore cutoff value of 2.7, respectively. The cutoffs correspond to an overall average FPR of 0.01, and result in an overall average TPR of 0.616 and 0.748 for VAST and SHEBA respectively. The x (target folds) and y (query folds) axes of the heat maps are labeled by the SCOP folds, grouped into the different classes A, B, C, D, E, F and G. Each pixel within the heat maps represents a fold-specific true or false positive rate and takes value between 0 and 1. Diagonal and off-diagonal pixels correspond to fold-specific true positive rate TPRi(c) (eq. 4, see Methods) and fold-specific false positive rate FPRi,j(c) (eq. 3, see Methods) respectively.

Format: PDF Size: 147KB Download file

This file can be viewed with: Adobe Acrobat Reader

Sam et al. BMC Bioinformatics 2006 7:206   doi:10.1186/1471-2105-7-206